Here's a full list of patches I'm running in Visual Studio.
I'm researching each of the Hotfix's to try and determine if any related to your Design Mode Exception.
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Microsoft Visual Studio 2008
Version 9.0.30729.1 SP
Microsoft .NET Framework
Version 3.5 SP1
Installed Edition: Professional
Microsoft Visual Basic 2008 * 91605-270-3900405-60054
Microsoft Visual Basic 2008
Microsoft Visual C# 2008 * 91605-270-3900405-60054
Microsoft Visual C# 2008
Microsoft Visual C++ 2008 * 91605-270-3900405-60054
Microsoft Visual C++ 2008
Microsoft Visual Studio 2008 Tools for Office * 91605-270-3900405-60054
Microsoft Visual Studio 2008 Tools for Office
Microsoft Visual Studio Tools for Applications 2.0 * 91605-270-3900405-60054
Microsoft Visual Studio Tools for Applications 2.0
Microsoft Visual Web Developer 2008 * 91605-270-3900405-60054
Microsoft Visual Web Developer 2008
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB944899) * KB944899
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/944899.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB945282) * KB945282
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/945282.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB946040) * KB946040
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/946040.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB946308) * KB946308
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/946308.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB946344) * KB946344
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/946344.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB946581) * KB946581
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/946581.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB947171) * KB947171
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947171.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB947173) * KB947173
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947173.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB947180) * KB947180
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947180.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB947540) * KB947540
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947540.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB947789) * KB947789
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947789.
Hotfix for Microsoft Visual Studio 2008 Professional Edition - ENU (KB948127) * KB948127
This hotfix is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this hotfix will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/948127.
Microsoft Visual Studio 2008 Professional Edition - ENU Service Pack 1 (KB945140) * KB945140
This service pack is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this service pack will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/945140.
Microsoft Visual Studio 2008 Professional Edition - ENU Service Pack 1 (KB947888) * KB947888
This service pack is for Microsoft Visual Studio 2008 Professional Edition - ENU.
If you later install a more recent service pack, this service pack will be uninstalled automatically.
For more information, visit http://support.microsoft.com/kb/947888.
Visual Studio Package Load Analyzer * 1.0
A utility that analyzes package load failures in Visual Studio.